As reported in Nature Medicine, Dr. Doris Taylor and her team at the University of Minnesota took the mouse heart and emptied their cells by bathing with detergent, That made retaining the structural heart tissue, including blood vessels, atrioventricular valves and geometry. Then they did was fill this structure with newly formed cardiac cells, which were grown in cultures that mimicked the physiology of the heart.
After four days, there was the existence of contractions, and eight days, they detected a bulge of 2% in adult heart. Now, what they lack in vivo test the effectiveness of the artificial heart. "When we see the first beat we were speechless," said Dr. Harald C. Ott, co-author.
This experiment was also repeated with a pig heart, and that has come out successfully. But this technique will take years to implement it in humans. But it will have to verify the functionality of this method in vivo, the transplantation of a bioartificial heart a laboratory animal, "the goal will then develop blood vessels or whole organs that are generated by the patient's own cells," said Taylor.
If this new development is successful, the combination of regenerative medicine and transplantation, will overcome three issues of great importance: the rejection, the organ shortage and the short survival time them. It is certainly a breakthrough in transplantation medicine.
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